Fast multidimensional localized parallel NMR spectroscopy for the analysis of samples

2010 John Wiley & Sons, Ltd.

Détails bibliographiques
Publié dans:Magnetic resonance in chemistry : MRC. - 1985. - 48(2010), 10 vom: 05. Okt., Seite 749-52
Auteur principal: Vega-Vazquez, Marino (Auteur)
Autres auteurs: Cobas, Juan Carlos, Martin-Pastor, Manuel
Format: Article en ligne
Langue:English
Publié: 2010
Accès à la collection:Magnetic resonance in chemistry : MRC
Sujets:Journal Article Research Support, Non-U.S. Gov't Nucleotides Sucrose 57-50-1
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520 |a A parallel localized spectroscopy (PALSY) method is presented to speed up the acquisition of multidimensional NMR (nD) spectra. The sample is virtually divided into a discrete number of nonoverlapping slices that relax independently during consecutive scans of the experiment, affording a substantial reduction in the interscan relaxation delay and the total experiment time. PALSY was tested for the acquisition of three experiments 2D COSY, 2D DQF-COSY and 2D TQF-COSY in parallel, affording a time-saving factor of 3-4. Some unique advantages are that the achievable resolution in any dimension is not compromised in any way: it uses conventional NMR data processing, it is not prone to generate spectral artifacts, and once calibrated, it can be used routinely with these and other combinations of NMR spectra 
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