Chlorination by-products of fenitrothion

The mutagens produced through chemical reaction between chlorine and the insecticide fenitrothion were studied by using a quadrupole GC-MS. The mutagenicity and the mutagen formation potential (MFP) of the identified by-products were evaluated by the Ames assay (preincubation method) using Salmonell...

Ausführliche Beschreibung

Bibliographische Detailangaben
Veröffentlicht in:Water science and technology : a journal of the International Association on Water Pollution Research. - 1986. - 62(2010), 1 vom: 18., Seite 85-91
1. Verfasser: Kishida, M (VerfasserIn)
Weitere Verfasser: Kumabe, T, Takanashi, H, Nakajima, T, Ohki, A, Miyake, Y, Kameya, T
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2010
Zugriff auf das übergeordnete Werk:Water science and technology : a journal of the International Association on Water Pollution Research
Schlagworte:Journal Article Insecticides Mutagens Fenitrothion W8M4X3Y7ZY
LEADER 01000caa a22002652 4500
001 NLM199270090
003 DE-627
005 20250211173046.0
007 cr uuu---uuuuu
008 231223s2010 xx |||||o 00| ||eng c
024 7 |a 10.2166/wst.2010.264  |2 doi 
028 5 2 |a pubmed25n0664.xml 
035 |a (DE-627)NLM199270090 
035 |a (NLM)20595757 
040 |a DE-627  |b ger  |c DE-627  |e rakwb 
041 |a eng 
100 1 |a Kishida, M  |e verfasserin  |4 aut 
245 1 0 |a Chlorination by-products of fenitrothion 
264 1 |c 2010 
336 |a Text  |b txt  |2 rdacontent 
337 |a ƒaComputermedien  |b c  |2 rdamedia 
338 |a ƒa Online-Ressource  |b cr  |2 rdacarrier 
500 |a Date Completed 28.09.2010 
500 |a Date Revised 21.11.2013 
500 |a published: Print 
500 |a Citation Status MEDLINE 
520 |a The mutagens produced through chemical reaction between chlorine and the insecticide fenitrothion were studied by using a quadrupole GC-MS. The mutagenicity and the mutagen formation potential (MFP) of the identified by-products were evaluated by the Ames assay (preincubation method) using Salmonella typhimurium TA100 without exogenous activation by S9 mix (TA100-S9). Before conducting GC/MS analyses, six compounds were presumed to be produced in chlorinated fenitrothion. These compounds were confirmed to be produced by the GC/MS analyses, but none of them were mutagenic. One of the chlorination by-products, 3-methyl-4-nitrophenol, has 19 times greater MFP than that of fenitrothion. This result suggests that a major mutagen in chlorinated fenitrothion will be produced via a chemical reaction between chlorine and 3-methyl-4-nitrophenol 
650 4 |a Journal Article 
650 7 |a Insecticides  |2 NLM 
650 7 |a Mutagens  |2 NLM 
650 7 |a Fenitrothion  |2 NLM 
650 7 |a W8M4X3Y7ZY  |2 NLM 
700 1 |a Kumabe, T  |e verfasserin  |4 aut 
700 1 |a Takanashi, H  |e verfasserin  |4 aut 
700 1 |a Nakajima, T  |e verfasserin  |4 aut 
700 1 |a Ohki, A  |e verfasserin  |4 aut 
700 1 |a Miyake, Y  |e verfasserin  |4 aut 
700 1 |a Kameya, T  |e verfasserin  |4 aut 
773 0 8 |i Enthalten in  |t Water science and technology : a journal of the International Association on Water Pollution Research  |d 1986  |g 62(2010), 1 vom: 18., Seite 85-91  |w (DE-627)NLM098149431  |x 0273-1223  |7 nnns 
773 1 8 |g volume:62  |g year:2010  |g number:1  |g day:18  |g pages:85-91 
856 4 0 |u http://dx.doi.org/10.2166/wst.2010.264  |3 Volltext 
912 |a GBV_USEFLAG_A 
912 |a SYSFLAG_A 
912 |a GBV_NLM 
912 |a GBV_ILN_350 
951 |a AR 
952 |d 62  |j 2010  |e 1  |b 18  |h 85-91