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231223s2010 xx |||||o 00| ||eng c |
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|a 10.2166/wst.2010.264
|2 doi
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|a pubmed25n0664.xml
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|a (NLM)20595757
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|a DE-627
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|e rakwb
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|a eng
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|a Kishida, M
|e verfasserin
|4 aut
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|a Chlorination by-products of fenitrothion
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|c 2010
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
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|a ƒa Online-Ressource
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|a Date Completed 28.09.2010
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|a Date Revised 21.11.2013
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|a published: Print
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|a Citation Status MEDLINE
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|a The mutagens produced through chemical reaction between chlorine and the insecticide fenitrothion were studied by using a quadrupole GC-MS. The mutagenicity and the mutagen formation potential (MFP) of the identified by-products were evaluated by the Ames assay (preincubation method) using Salmonella typhimurium TA100 without exogenous activation by S9 mix (TA100-S9). Before conducting GC/MS analyses, six compounds were presumed to be produced in chlorinated fenitrothion. These compounds were confirmed to be produced by the GC/MS analyses, but none of them were mutagenic. One of the chlorination by-products, 3-methyl-4-nitrophenol, has 19 times greater MFP than that of fenitrothion. This result suggests that a major mutagen in chlorinated fenitrothion will be produced via a chemical reaction between chlorine and 3-methyl-4-nitrophenol
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|a Journal Article
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|a Insecticides
|2 NLM
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|a Mutagens
|2 NLM
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|a Fenitrothion
|2 NLM
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|a W8M4X3Y7ZY
|2 NLM
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|a Kumabe, T
|e verfasserin
|4 aut
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|a Takanashi, H
|e verfasserin
|4 aut
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|a Nakajima, T
|e verfasserin
|4 aut
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|a Ohki, A
|e verfasserin
|4 aut
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|a Miyake, Y
|e verfasserin
|4 aut
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|a Kameya, T
|e verfasserin
|4 aut
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|i Enthalten in
|t Water science and technology : a journal of the International Association on Water Pollution Research
|d 1986
|g 62(2010), 1 vom: 18., Seite 85-91
|w (DE-627)NLM098149431
|x 0273-1223
|7 nnns
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|g volume:62
|g year:2010
|g number:1
|g day:18
|g pages:85-91
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|u http://dx.doi.org/10.2166/wst.2010.264
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