Adaptation and validation of DNA synthesis detection by fluorescent dye derivatization for high-throughput screening

Cellular proliferation is fundamental to organism development, tissue renewal, and diverse disease states such as cancer. In vitro measurement of proliferation by high-throughput screening allows rapid characterization of the effects of small-molecule or genetic treatments on primary and established...

Ausführliche Beschreibung

Bibliographische Detailangaben
Veröffentlicht in:BioTechniques. - 1988. - 48(2010), 5 vom: 01. Mai, Seite 379-86
1. Verfasser: Ranall, Max V (VerfasserIn)
Weitere Verfasser: Gabrielli, Brian G, Gonda, Thomas J
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2010
Zugriff auf das übergeordnete Werk:BioTechniques
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Validation Study Fluorescent Dyes Indoles Protein Kinase Inhibitors DAPI 47165-04-8 Epidermal Growth Factor 62229-50-9 mehr... DNA 9007-49-2 5-ethynyl-2'-deoxyuridine G373S00W2J Deoxyuridine W78I7AY22C