Beta-carboline alkaloids from the stems of Picrasma quassioides

Copyright (c) 2010 John Wiley & Sons, Ltd.

Bibliographische Detailangaben
Veröffentlicht in:Magnetic resonance in chemistry : MRC. - 1985. - 48(2010), 6 vom: 21. Juni, Seite 490-5
1. Verfasser: Jiao, Wei-Hua (VerfasserIn)
Weitere Verfasser: Gao, Hao, Li, Chen-Yang, Zhou, Guang-Xiong, Kitanaka, Susumu, Ohmura, Atsuko, Yao, Xin-Sheng
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2010
Zugriff auf das übergeordnete Werk:Magnetic resonance in chemistry : MRC
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Alkaloids Carbolines Plant Extracts
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520 |a Five new beta-carboline alkaloids, 6,12-dimethoxy-3-(2-hydroxylethyl)-beta-carboline (1), 3,10-dihydroxy-beta-carboline (2), 6,12-dimethoxy-3-(1-hydroxylethyl)-beta-carboline (3), 6,12-dimethoxy-3-(1,2-dihydroxylethyl)-beta-carboline (4), and 6-methoxy-3-(2-hydroxyl-1-ethoxylethyl)-beta-carboline (5), and two new natural products, 6-methoxy-12-hydroxy-3-methoxycarbonyl-beta-carboline (6) and 3-hydroxy-beta-carboline (7) were isolated from the stems of Picrasma quassioides along with 16 known beta-carboline alkaloids (8-23). The structures of new compounds were determined by extensive spectroscopic analyses, and the 1D and 2D NMR data of compounds 6, 7 and 10 were reported for the first time. The bioassays showed that only compounds 14 and 16 could enhance the differentiation of 3T3-L1 preadiocytes accompanied by secretion of adiponectin proteins among these 23 compounds 
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700 1 |a Li, Chen-Yang  |e verfasserin  |4 aut 
700 1 |a Zhou, Guang-Xiong  |e verfasserin  |4 aut 
700 1 |a Kitanaka, Susumu  |e verfasserin  |4 aut 
700 1 |a Ohmura, Atsuko  |e verfasserin  |4 aut 
700 1 |a Yao, Xin-Sheng  |e verfasserin  |4 aut 
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