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231223s2010 xx |||||o 00| ||eng c |
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|a 10.1002/mrc.2602
|2 doi
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|a pubmed24n0660.xml
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|a (NLM)20474029
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|a DE-627
|b ger
|c DE-627
|e rakwb
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|a eng
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|a Jiao, Wei-Hua
|e verfasserin
|4 aut
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|a Beta-carboline alkaloids from the stems of Picrasma quassioides
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|c 2010
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
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|2 rdamedia
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|a ƒa Online-Ressource
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|a Date Completed 13.09.2010
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|a Date Revised 17.05.2010
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|a published: Print
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|a Citation Status MEDLINE
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|a Copyright (c) 2010 John Wiley & Sons, Ltd.
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|a Five new beta-carboline alkaloids, 6,12-dimethoxy-3-(2-hydroxylethyl)-beta-carboline (1), 3,10-dihydroxy-beta-carboline (2), 6,12-dimethoxy-3-(1-hydroxylethyl)-beta-carboline (3), 6,12-dimethoxy-3-(1,2-dihydroxylethyl)-beta-carboline (4), and 6-methoxy-3-(2-hydroxyl-1-ethoxylethyl)-beta-carboline (5), and two new natural products, 6-methoxy-12-hydroxy-3-methoxycarbonyl-beta-carboline (6) and 3-hydroxy-beta-carboline (7) were isolated from the stems of Picrasma quassioides along with 16 known beta-carboline alkaloids (8-23). The structures of new compounds were determined by extensive spectroscopic analyses, and the 1D and 2D NMR data of compounds 6, 7 and 10 were reported for the first time. The bioassays showed that only compounds 14 and 16 could enhance the differentiation of 3T3-L1 preadiocytes accompanied by secretion of adiponectin proteins among these 23 compounds
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|a Journal Article
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|a Research Support, Non-U.S. Gov't
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|a Alkaloids
|2 NLM
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|a Carbolines
|2 NLM
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|a Plant Extracts
|2 NLM
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|a Gao, Hao
|e verfasserin
|4 aut
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|a Li, Chen-Yang
|e verfasserin
|4 aut
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|a Zhou, Guang-Xiong
|e verfasserin
|4 aut
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|a Kitanaka, Susumu
|e verfasserin
|4 aut
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|a Ohmura, Atsuko
|e verfasserin
|4 aut
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|a Yao, Xin-Sheng
|e verfasserin
|4 aut
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|i Enthalten in
|t Magnetic resonance in chemistry : MRC
|d 1985
|g 48(2010), 6 vom: 21. Juni, Seite 490-5
|w (DE-627)NLM098179667
|x 1097-458X
|7 nnns
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|g volume:48
|g year:2010
|g number:6
|g day:21
|g month:06
|g pages:490-5
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|u http://dx.doi.org/10.1002/mrc.2602
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