Stimuli-responsive porous hydrogels at interfaces for molecular filtration, separation, controlled release, and gating in capsules and membranes
A continuously growing area of controlled and tunable transport and separation of biomolecules and drugs has recently attracted attention to the structures which can be referred to as stimuli-responsive porous hydrogel thin films. Because of spatial constraints, swelling/shrinking of the hydrogel fi...
| Publié dans: | Advanced materials (Deerfield Beach, Fla.). - 1998. - 22(2010), 31 vom: 17. Aug., Seite 3446-62 |
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| Format: | Article en ligne |
| Langue: | English |
| Publié: |
2010
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| Accès à la collection: | Advanced materials (Deerfield Beach, Fla.) |
| Sujets: | Journal Article Research Support, U.S. Gov't, Non-P.H.S. Review Capsules Hydrogels Membranes, Artificial Solvents |
| Résumé: | A continuously growing area of controlled and tunable transport and separation of biomolecules and drugs has recently attracted attention to the structures which can be referred to as stimuli-responsive porous hydrogel thin films. Because of spatial constraints, swelling/shrinking of the hydrogel films results in closing/opening (or vice versa) of the film's pores. Such responsive systems can be used in the configuration of plane films or capsules. The combination of a low thickness (translating into a low hydrodynamic flow resistance and rapid response) with well-defined size and shape of pores (translating into better control of transport and separation), which can be closed, opened, or tuned by an external signal (allowing a large amplitude of changes in diffusivity of solutes in the thin film and a precise control of the pore size), makes these materials very attractive for a range of applications, such as molecular filtration, separation, drug delivery, sensors, and actuators |
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| Description: | Date Completed 22.11.2010 Date Revised 30.09.2020 published: Print Citation Status MEDLINE |
| ISSN: | 1521-4095 |
| DOI: | 10.1002/adma.201000165 |