Epithelial-specific blockade of MyD88-dependent pathway causes spontaneous small intestinal inflammation

Accumulating evidence suggests a role for Toll-like receptor (TLR) signaling at the intestinal epithelial cells (IECs) level for intestinal protection against exogenous injury or pathogenic infection. We hypothesized that MyD88 dependent TLR signaling at intestinal epithelium is critical for mucosal...

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Bibliographische Detailangaben

Veröffentlicht in:	Clinical immunology (Orlando, Fla.). - 1999. - 136(2010), 2 vom: 01. Aug., Seite 245-56
1. Verfasser:	Gong, Jianfeng (VerfasserIn)
Weitere Verfasser:	Xu, Jingyue, Zhu, Weiming, Gao, Xiang, Li, Ning, Li, Jieshou
Format:	Online-Aufsatz
Sprache:	English
Veröffentlicht:	2010
Zugriff auf das übergeordnete Werk:	Clinical immunology (Orlando, Fla.)
Schlagworte:	Journal Article Research Support, Non-U.S. Gov't Antimicrobial Cationic Peptides Cytokines Lipopolysaccharides Microfilament Proteins Myd88 protein, mouse Myeloid Differentiation Factor 88 NF-kappa B villin