A protective role of Mer receptor tyrosine kinase in nephrotoxic serum-induced nephritis

The Mer receptor tyrosine kinase is strongly expressed in the glomerulus. We wondered if this molecule might modify immune-mediated glomerular disease through its functions as a receptor for apoptotic cells and immunoregulatory molecule. Mer-knockout (KO) mice showed decreased survival rate and grea...

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Veröffentlicht in:	Clinical immunology (Orlando, Fla.). - 1999. - 136(2010), 2 vom: 15. Aug., Seite 236-44
1. Verfasser:	Shao, Wen-Hai (VerfasserIn)
Weitere Verfasser:	Zhen, Yuxuan, Rosenbaum, Joshua, Eisenberg, Robert A, McGaha, Tracy L, Birkenbach, Mark, Cohen, Philip L
Format:	Online-Aufsatz
Sprache:	English
Veröffentlicht:	2010
Zugriff auf das übergeordnete Werk:	Clinical immunology (Orlando, Fla.)
Schlagworte:	Journal Article Research Support, U.S. Gov't, Non-P.H.S. Ccl2 protein, mouse Chemokine CCL2 Cytokines Immune Sera Proto-Oncogene Proteins Tumor Necrosis Factor-alpha Mertk protein, mouse EC 2.7.10.1 mehr... Receptor Protein-Tyrosine Kinases c-Mer Tyrosine Kinase