Effects of the novel immunosuppressant FTY720 in a murine rheumatoid arthritis model

We investigated the effects and mechanisms by which FTY720 (FTY) inhibits arthritis development in the SKG mouse rheumatoid arthritis (RA) model. FTY (1mg/kg/day) administration suppressed the progression of laminarin-induced arthritis in SKG mice. FTY treatment decreased IL-6 and TNF-alpha expressi...

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Publié dans:Clinical immunology (Orlando, Fla.). - 1999. - 136(2010), 2 vom: 15. Aug., Seite 197-204
Auteur principal: Tsunemi, Sachi (Auteur)
Autres auteurs: Iwasaki, Tsuyoshi, Kitano, Sachie, Imado, Takehito, Miyazawa, Keiji, Sano, Hajime
Format: Article en ligne
Langue:English
Publié: 2010
Accès à la collection:Clinical immunology (Orlando, Fla.)
Sujets:Journal Article Research Support, Non-U.S. Gov't Cytokines Glucans Immunosuppressive Agents Polysaccharides Propylene Glycols Interleukin-4 207137-56-2 laminaran plus... 9008-22-4 Fingolimod Hydrochloride G926EC510T Dinoprostone K7Q1JQR04M Sphingosine NGZ37HRE42