The use of extracorporeal membrane oxygenation in sustaining pulmonary function patients with influenza A H1N1

OBJECTIVE: To summarize the clinical method and initial experience of extracorporeal membrane oxygenation (ECMO) supportive treatment in influenza A H1N1 serious patients

Bibliographische Detailangaben
Veröffentlicht in:Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue. - 1998. - 22(2010), 3 vom: 06. März, Seite 161-3
1. Verfasser: Duan, Da-wei (VerfasserIn)
Weitere Verfasser: Li, Tong, Qin, Ying-zhi, Xu, Lei, Zhao, Cheng-xiu, Hu, Xiao-min, Wu, Peng, Zhang, Qiang, Lang, Yu-heng
Format: Aufsatz
Sprache:Chinese
Veröffentlicht: 2010
Zugriff auf das übergeordnete Werk:Zhongguo wei zhong bing ji jiu yi xue = Chinese critical care medicine = Zhongguo weizhongbing jijiuyixue
Schlagworte:English Abstract Journal Article
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520 |a OBJECTIVE: To summarize the clinical method and initial experience of extracorporeal membrane oxygenation (ECMO) supportive treatment in influenza A H1N1 serious patients 
520 |a METHODS: In 5 critically ill patients with influenza A H1N1, their arterial oxygen saturation was 0.70 to 0.85 with oxygen concentration (FiO(2)) 1.00 under mechanical ventilation. In these 5 patients, 3 males and 2 females, vein-vein mode ECMO bypass (femoral vein-internal jugular vein) was carried out to assist pulmonary function. The ratio between ECMO oxygen flow and blood flow was 2-1:1, FiO(2) was 0.21 to 1.00, FiO(2) for mechanical ventilation was 0.30 to 0.70, and positive end expiratory pressure (PEEP) was 5-10 cm H(2)O (1 cm H(2)O= 0.098 kPa). Activated coagulation time (ACT) was maintained at 160-250 s. When artery oxygen saturation and artery-venous blood gas became normal on discontinuation of ECMO, ECMO was weaned, and venous cannulas were removed. Mechanical ventilation was continued 
520 |a RESULTS: In 5 patients the assisting time of ECMO was 48-330 hours, the mean duration was 178.2 hours. ECMO assisted flow was 2.4-4.0 L/min. The observation time after stoppage of ECMO was 4-24 hours. Four patients were weaned from ECMO, with continuation of assisted respiration successfully. One patient died because the family member gave up hope and the treatment was stopped 
520 |a CONCLUSION: Vein-vein mode ECMO bypass through femoral vein-internal jugular vein can offer effective aid to pulmonary function in influenza A H1N1 patients who are critically ill. The strategy can win time for the patients to be able to continue mechanical ventilation treatment 
650 4 |a English Abstract 
650 4 |a Journal Article 
700 1 |a Li, Tong  |e verfasserin  |4 aut 
700 1 |a Qin, Ying-zhi  |e verfasserin  |4 aut 
700 1 |a Xu, Lei  |e verfasserin  |4 aut 
700 1 |a Zhao, Cheng-xiu  |e verfasserin  |4 aut 
700 1 |a Hu, Xiao-min  |e verfasserin  |4 aut 
700 1 |a Wu, Peng  |e verfasserin  |4 aut 
700 1 |a Zhang, Qiang  |e verfasserin  |4 aut 
700 1 |a Lang, Yu-heng  |e verfasserin  |4 aut 
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