Encapsulation of a hydrophobic drug into a polymer-micelle core explored with synchrotron SAXS

Synchrotron small-angle X-ray scattering (SAXS) at the SPring-8 40B2 and 45XU beamlines was carried out on aqueous solutions of (PEG-P(Asp(Bzl))): partially benzyl-esterified poly(ethylene glycol)-block-poly(aspartic acid) with LE540 loaded up to 8.3 wt %, where LE540 is a very hydrophobic retinoid...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 26(2010), 10 vom: 18. Mai, Seite 7544-51
1. Verfasser: Akiba, Isamu (VerfasserIn)
Weitere Verfasser: Terada, Naotaka, Hashida, Satoshi, Sakurai, Kazuo, Sato, Taku, Shiraishi, Kouichi, Yokoyama, Masayuki, Masunaga, Hiroyasu, Ogawa, Hiroki, Ito, Kazuki, Yagi, Naoto
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2010
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Dibenzazepines LE 540 Micelles polyethylene glycol-block-polyaspartic acid Polyethylene Glycols 3WJQ0SDW1A