Immobilization of peptides with distinct biological activities onto stem cell culture substrates using orthogonal chemistries

We have used the orthogonal carbodiimide condensation and copper-catalyzed azide-alkyne "click" cycloaddition (CuAAC) reactions to prepare self-assembled monolayers that present distinct peptides to stem cells in a bioinert background. The approach involved first forming mixed SAMs with th...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 26(2010), 9 vom: 04. Mai, Seite 6449-56
1. Verfasser: Hudalla, Gregory A (VerfasserIn)
Weitere Verfasser: Murphy, William L
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2010
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, N.I.H., Extramural Research Support, U.S. Gov't, Non-P.H.S. Amines Azides Carbodiimides Immobilized Proteins Integrins Ligands Oligopeptides mehr... Proteoglycans heparin proteoglycan Polyethylene Glycols 3WJQ0SDW1A Copper 789U1901C5 Heparin 9005-49-6 Acetylene OC7TV75O83