Isomer-dependent adsorption and release of cis- and trans-platin anticancer drugs by mesoporous silica nanoparticles

We report on adsorption and release of the anticancer drugs cisplatin and transplatin from mesoporous silica nanomaterials, emphasizing the differences between cisplatin and its much less toxic isomer. Two types of particles, MCM-41 and SBA-15, were used, either as just synthesized or after calcinat...

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Veröffentlicht in:	Langmuir : the ACS journal of surfaces and colloids. - 1999. - 26(2010), 11 vom: 01. Juni, Seite 8914-24
1. Verfasser:	Tao, Zhimin (VerfasserIn)
Weitere Verfasser:	Xie, Youwei, Goodisman, Jerry, Asefa, Tewodros
Format:	Online-Aufsatz
Sprache:	English
Veröffentlicht:	2010
Zugriff auf das übergeordnete Werk:	Langmuir : the ACS journal of surfaces and colloids
Schlagworte:	Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Antineoplastic Agents transplatin 14913-33-8 Silicon Dioxide 7631-86-9 Cisplatin Q20Q21Q62J