Effect of hydrophobic interactions on properties and stability of DNA-polyelectrolyte complexes

Polyplexes are polyelectrolyte complexes of DNA and polycations, designed for potential gene delivery. We investigated the properties of new polyplexes formed from cholesterol-modified polycations and DNA. Three complexes were tested; their cholesterol contents were 1.4, 6.3, and 8.7 mol %. UV spect...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 26(2010), 7 vom: 06. Apr., Seite 4999-5006
1. Verfasser: Filippov, Sergey K (VerfasserIn)
Weitere Verfasser: Konák, Cestmír, Kopecková, Pavla, Starovoytova, Larisa, Spírková, Milena, Stepánek, Petr
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2010
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Polyamines Polyelectrolytes polycations DNA 9007-49-2