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231223s2009 xx |||||o 00| ||eng c |
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|a pubmed25n0647.xml
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|a (DE-627)NLM194129837
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|a (NLM)20050040
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|a DE-627
|b ger
|c DE-627
|e rakwb
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|a eng
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| 100 |
1 |
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|a Liang, Gaolin
|e verfasserin
|4 aut
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| 245 |
1 |
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|a Supramolecular hydrogel of a D-amino acid dipeptide for controlled drug release in vivo
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| 264 |
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|c 2009
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| 336 |
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|a Text
|b txt
|2 rdacontent
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| 337 |
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|a ƒaComputermedien
|b c
|2 rdamedia
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| 338 |
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|a ƒa Online-Ressource
|b cr
|2 rdacarrier
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| 500 |
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|a Date Completed 19.01.2010
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| 500 |
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|a Date Revised 27.10.2019
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|a published: Print
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|a Citation Status MEDLINE
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| 520 |
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|a A supramolecular hydrogel based on D-amino acids, which resists hydrolysis catalyzed by proteinase K and offers long-term biostability, exhibits controlled release in vivo, as proved by the pharmacokinetics of encapsulated 125I tracers and the SPECT imaging of the hydrogel-encapsulated 131I tracers. As the first in vivo imaging investigation of the drug release properties of the supramolecular hydrogel, isotope encapsulation serves as a valid, useful assay for characterizing the controlled release properties of supramolecular hydrogels in vivo. Our results indicate that supramolecular hydrogels promise new biomaterials for controlled drug release
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4 |
|a Journal Article
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| 650 |
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4 |
|a Research Support, Non-U.S. Gov't
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| 650 |
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7 |
|a Amino Acids
|2 NLM
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| 650 |
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7 |
|a Biocompatible Materials
|2 NLM
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| 650 |
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7 |
|a Dipeptides
|2 NLM
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| 650 |
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7 |
|a Drug Carriers
|2 NLM
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| 650 |
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7 |
|a Hydrogels
|2 NLM
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| 650 |
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7 |
|a Iodine Radioisotopes
|2 NLM
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| 650 |
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7 |
|a Hydrogel, Polyethylene Glycol Dimethacrylate
|2 NLM
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| 650 |
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7 |
|a 25852-47-5
|2 NLM
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| 650 |
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7 |
|a Sodium Iodide
|2 NLM
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| 650 |
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7 |
|a F5WR8N145C
|2 NLM
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| 700 |
1 |
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|a Yang, Zhimou
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Zhang, Rongjun
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Li, Lihua
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Fan, Yijun
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Kuang, Yi
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Gao, Yuan
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Wang, Ting
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Lu, W William
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Xu, Bing
|e verfasserin
|4 aut
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| 773 |
0 |
8 |
|i Enthalten in
|t Langmuir : the ACS journal of surfaces and colloids
|d 1991
|g 25(2009), 15 vom: 04. Aug., Seite 8419-22
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|g volume:25
|g year:2009
|g number:15
|g day:04
|g month:08
|g pages:8419-22
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|d 25
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