Colorimetric sensing of alpha-amino acids and its application for the "label-free" detection of protease

A new indirect approach to explore sensitive colorimetric sensors toward alpha-amino acids is proposed: the pink solution of 1 and copper ions changed to colorless immediately upon the addition of alpha-amino acids. As the hydrolysis of bovine serum albumin (BSA) with the aid of trypsin produces alp...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 26(2010), 3 vom: 02. Feb., Seite 1566-9
1. Verfasser: Lou, Xiaoding (VerfasserIn)
Weitere Verfasser: Zhang, Liyao, Qin, Jingui, Li, Zhen
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2010
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Amino Acids Rhodamines Serum Albumin, Bovine 27432CM55Q Copper 789U1901C5 Peptide Hydrolases EC 3.4.- mehr... rhodamine B K7G5SCF8IL
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245 1 0 |a Colorimetric sensing of alpha-amino acids and its application for the "label-free" detection of protease 
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520 |a A new indirect approach to explore sensitive colorimetric sensors toward alpha-amino acids is proposed: the pink solution of 1 and copper ions changed to colorless immediately upon the addition of alpha-amino acids. As the hydrolysis of bovine serum albumin (BSA) with the aid of trypsin produces alpha-amino acids, the complex of 1/Cu(2+)/BSA could act as a label-free, sensitive, selective sensor toward trypsin. The detection process could be visually observed by naked eyes 
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700 1 |a Li, Zhen  |e verfasserin  |4 aut 
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