Designed surface with tunable IgG density as an in vitro model for immune complex mediated stimulation of leukocytes

We present the design of an in vitro model for immune-complex-mediated stimulation of leukocytes and its functional characteristics with respect to monocyte adhesion. The model was based on the orientation-controlled immobilization of a humanized IgG1 monoclonal antibody (rituximab) via its interact...

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Bibliographische Detailangaben
Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 26(2010), 5 vom: 02. März, Seite 3493-7
1. Verfasser: Kanmert, Daniel (VerfasserIn)
Weitere Verfasser: Enocsson, Helena, Wetterö, Jonas, Kastbom, Alf, Skogh, Thomas, Enander, Karin
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2010
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Alkanes Antibodies, Immobilized Antibodies, Monoclonal Antibodies, Monoclonal, Murine-Derived Antigen-Antibody Complex Antigens, CD20 Disulfides Epitopes mehr... Immunoglobulin G Peptide Fragments Receptors, IgG Polyethylene Glycols 3WJQ0SDW1A Rituximab 4F4X42SYQ6 Gold 7440-57-5