Facile disassembly of amyloid fibrils using gemini surfactant micelles

The accumulation of a peptide of 38-43 amino acids, in the form of fibrillar plaques, was one of the essential reasons for Alzheimer's disease (AD). Discovering an agent that is able to disassemble and clear disease-associated Abeta peptide fibrils from the brains of AD patients would have crit...

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Publié dans:Langmuir : the ACS journal of surfaces and colloids. - 1985. - 26(2010), 3 vom: 02. Feb., Seite 1583-7
Auteur principal: Han, Yuchun (Auteur)
Autres auteurs: He, Chengqian, Cao, Meiwen, Huang, Xu, Wang, Yilin, Li, Zhibo
Format: Article en ligne
Langue:English
Publié: 2010
Accès à la collection:Langmuir : the ACS journal of surfaces and colloids
Sujets:Journal Article Research Support, Non-U.S. Gov't Alkenes Amyloid beta-Peptides Micelles Peptide Fragments Quaternary Ammonium Compounds Surface-Active Agents amyloid beta-protein (1-40) hexamethylene-1,6-bis(dodecyldimethylammonium bromide)