Facile disassembly of amyloid fibrils using gemini surfactant micelles
The accumulation of a peptide of 38-43 amino acids, in the form of fibrillar plaques, was one of the essential reasons for Alzheimer's disease (AD). Discovering an agent that is able to disassemble and clear disease-associated Abeta peptide fibrils from the brains of AD patients would have crit...
Ausführliche Beschreibung
Bibliographische Detailangaben
Veröffentlicht in: | Langmuir : the ACS journal of surfaces and colloids. - 1985. - 26(2010), 3 vom: 02. Feb., Seite 1583-7
|
1. Verfasser: |
Han, Yuchun
(VerfasserIn) |
Weitere Verfasser: |
He, Chengqian,
Cao, Meiwen,
Huang, Xu,
Wang, Yilin,
Li, Zhibo |
Format: | Online-Aufsatz
|
Sprache: | English |
Veröffentlicht: |
2010
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Zugriff auf das übergeordnete Werk: | Langmuir : the ACS journal of surfaces and colloids
|
Schlagworte: | Journal Article
Research Support, Non-U.S. Gov't
Alkenes
Amyloid beta-Peptides
Micelles
Peptide Fragments
Quaternary Ammonium Compounds
Surface-Active Agents
amyloid beta-protein (1-40)
hexamethylene-1,6-bis(dodecyldimethylammonium bromide) |