A dual-activation, adenoviral-based system for the controlled induction of DNA double-strand breaks by the restriction endonuclease SacI 
    
    
              
              Spontaneous damage to DNA is frequent and may lead to cell death, cell senescence, or mutations. DNA double-strand breaks (DSBs) are of special interest because they are highly toxic and have been implicated in neurodegeneration, cancer, and aging. Until now, there has not been a reliable system all...
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        Détails bibliographiques
                  | Publié dans: | BioTechniques. - 1991. - 47(2009), 4 vom: 23. Okt., Seite 847-54 
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                  | Auteur principal: | Maslov, Alexander Y
      (Auteur) | 
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                  | Autres auteurs: | Metrikin, Maya, 
      
        Vijg, Jan | 
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                  | Format: | Article en ligne | 
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                  | Langue: | English | 
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                  | Publié: | 2009 
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                  | Accès à la collection: | BioTechniques 
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                  | Sujets: | Journal Article
            Research Support, N.I.H., Extramural
            Research Support, Non-U.S. Gov't
            Anti-Bacterial Agents
            Coloring Agents
            Selective Estrogen Receptor Modulators
            Tetrazolium Salts
            Thiazoles
            Tamoxifen
            094ZI81Y45
        plus...
            DNA
            9007-49-2
            endodeoxyribonuclease SacI
            EC 3.1.21.-
            Deoxyribonucleases, Type II Site-Specific
            EC 3.1.21.4
            thiazolyl blue
            EUY85H477I
            Doxycycline
            N12000U13O | 
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