A novel method for sensitive and specific detection of DNA methylation biomarkers based on DNA restriction during PCR cycling
DNA methylation is an important epigenetic mechanism involved in fundamental biological processes such as development, imprinting, and carcino-genesis. For these reasons, DNA methylation represents a valuable source for cancer biomarkers. Methods for the sensitive and specific detection of methylate...
Ausführliche Beschreibung
Bibliographische Detailangaben
Veröffentlicht in: | BioTechniques. - 1993. - 47(2009), 3 vom: 23. Sept., Seite 737-44
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1. Verfasser: |
Kneip, Christoph
(VerfasserIn) |
Weitere Verfasser: |
Schmidt, Bernd,
Fleischhacker, Michael,
Seegebarth, Anke,
Lewin, Jörn,
Flemming, Nadja,
Seemann, Stefanie,
Schlegel, Thomas,
Witt, Christian,
Liebenberg, Volker,
Dietrich, Dimo |
Format: | Online-Aufsatz
|
Sprache: | English |
Veröffentlicht: |
2009
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Zugriff auf das übergeordnete Werk: | BioTechniques
|
Schlagworte: | Evaluation Study
Journal Article
BARHL2 protein, human
Biomarkers, Tumor
DNA, Neoplasm
Homeodomain Proteins
Nerve Tissue Proteins
DNA Restriction Enzymes
EC 3.1.21.- |