A novel method for sensitive and specific detection of DNA methylation biomarkers based on DNA restriction during PCR cycling

DNA methylation is an important epigenetic mechanism involved in fundamental biological processes such as development, imprinting, and carcino-genesis. For these reasons, DNA methylation represents a valuable source for cancer biomarkers. Methods for the sensitive and specific detection of methylate...

Ausführliche Beschreibung

Bibliographische Detailangaben
Veröffentlicht in:BioTechniques. - 1993. - 47(2009), 3 vom: 23. Sept., Seite 737-44
1. Verfasser: Kneip, Christoph (VerfasserIn)
Weitere Verfasser: Schmidt, Bernd, Fleischhacker, Michael, Seegebarth, Anke, Lewin, Jörn, Flemming, Nadja, Seemann, Stefanie, Schlegel, Thomas, Witt, Christian, Liebenberg, Volker, Dietrich, Dimo
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2009
Zugriff auf das übergeordnete Werk:BioTechniques
Schlagworte:Evaluation Study Journal Article BARHL2 protein, human Biomarkers, Tumor DNA, Neoplasm Homeodomain Proteins Nerve Tissue Proteins DNA Restriction Enzymes EC 3.1.21.-