Imbibition in porous membranes of complex shape : quasi-stationary flow in thin rectangular segments

The sustained liquid flow of a typical lateral flow assay can be mimicked by two-dimensional shaped, thin porous membranes, specifically rectangular membranes appended to circular sectors. In designing these fan-shaped devices, we have been aided by analytical equations and finite-element simulation...

Ausführliche Beschreibung

Bibliographische Detailangaben
Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 26(2010), 2 vom: 19. Jan., Seite 1380-5
1. Verfasser: Mendez, Sergio (VerfasserIn)
Weitere Verfasser: Fenton, Erin M, Gallegos, Gil R, Petsev, Dimiter N, Sibbett, Scott S, Stone, Howard A, Zhang, Yi, López, Gabriel P
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2010
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, U.S. Gov't, Non-P.H.S. Membranes, Artificial
Beschreibung
Zusammenfassung:The sustained liquid flow of a typical lateral flow assay can be mimicked by two-dimensional shaped, thin porous membranes, specifically rectangular membranes appended to circular sectors. In designing these fan-shaped devices, we have been aided by analytical equations and finite-element simulations. We show both mathematically and experimentally how a continuous increase in unwetted pore volume causes a deviation from traditional imbibition, and leads to quasi-stationary flow in the rectangular element. These results are both theoretically and practically important because they indicate how medical diagnostic test strips may be fabricated without incorporating an absorbent pad
Beschreibung:Date Completed 11.03.2010
Date Revised 13.01.2010
published: Print
Citation Status MEDLINE
ISSN:1520-5827
DOI:10.1021/la902470b