Low viscosity highly concentrated injectable nonaqueous suspensions of lysozyme microparticles

Subcutaneous injection of concentrated protein and peptide solutions, in the range of 100-400 mg/mL, is often not possible with a 25- to 27-gauge needle, as the viscosity can be well above 50 cP. Apparent viscosities below this limit are reported for suspensions of milled lysozyme microparticles up...

Ausführliche Beschreibung

Bibliographische Detailangaben
Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 26(2010), 2 vom: 19. Jan., Seite 1067-74
1. Verfasser: Miller, Maria A (VerfasserIn)
Weitere Verfasser: Engstrom, Joshua D, Ludher, Baltej S, Johnston, Keith P
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2010
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Benzoates Suspensions Safflower Oil 8001-23-8 Muramidase EC 3.2.1.17 mehr... benzyl benzoate N863NB338G