Characterization of a dammarenediol synthase in Centella asiatica (L.) Urban

To elucidate the exact function of CabAS in Centella asiatica, which was previously reported as a putative beta-amyrin synthase [Plant Cell Rep, 24:304-311, 2005], this gene was functionally expressed in the lanosterol synthase-deficient yeast mutant (erg7). After inducing the CabAS gene with galact...

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Veröffentlicht in:Plant physiology and biochemistry : PPB. - 1991. - 47(2009), 11-12 vom: 01. Nov., Seite 998-1002
1. Verfasser: Kim, Ok Tae (VerfasserIn)
Weitere Verfasser: Lee, Jei Wan, Bang, Kyong Hwan, Kim, Young Chang, Hyun, Dong Yun, Cha, Seon Woo, Choi, Yong Eui, Jin, Mei Lan, Hwang, Baik
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2009
Zugriff auf das übergeordnete Werk:Plant physiology and biochemistry : PPB
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Plant Proteins Saponins Triterpenes dammarenediol 14351-29-2 Alkyl and Aryl Transferases EC 2.5.- Intramolecular Transferases mehr... EC 5.4.- lanosterol synthase EC 5.4.99.7 Galactose X2RN3Q8DNE
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520 |a To elucidate the exact function of CabAS in Centella asiatica, which was previously reported as a putative beta-amyrin synthase [Plant Cell Rep, 24:304-311, 2005], this gene was functionally expressed in the lanosterol synthase-deficient yeast mutant (erg7). After inducing the CabAS gene with galactose, a peak consistent with the dammarenediol standard was detected in LC/APCIMS analyses and the accumulated product was confirmed as dammarenediol. CabAS should therefore be renamed to C. asiatica dammarenediol synthase (CaDDS). The confirmation of this gene function may allow us to better understand the generation of numerous triterpene carbon skeletons 
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650 7 |a X2RN3Q8DNE  |2 NLM 
700 1 |a Lee, Jei Wan  |e verfasserin  |4 aut 
700 1 |a Bang, Kyong Hwan  |e verfasserin  |4 aut 
700 1 |a Kim, Young Chang  |e verfasserin  |4 aut 
700 1 |a Hyun, Dong Yun  |e verfasserin  |4 aut 
700 1 |a Cha, Seon Woo  |e verfasserin  |4 aut 
700 1 |a Choi, Yong Eui  |e verfasserin  |4 aut 
700 1 |a Jin, Mei Lan  |e verfasserin  |4 aut 
700 1 |a Hwang, Baik  |e verfasserin  |4 aut 
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