Cause and effect of melittin-induced pore formation : a computational approach

Melittin embedded in a palmitoyl oleyl phosphatidylcholine bilayer at a high peptide/lipid ratio (1:30) was simulated in the presence of explicit water and ions. The simulation results indicate the incipience of an ion-permeable water pore through collective membrane perturbation by bound peptides....

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Détails bibliographiques
Publié dans:Langmuir : the ACS journal of surfaces and colloids. - 1991. - 25(2009), 20 vom: 20. Okt., Seite 12235-42
Auteur principal: Manna, Moutusi (Auteur)
Autres auteurs: Mukhopadhyay, Chaitali
Format: Article en ligne
Langue:English
Publié: 2009
Accès à la collection:Langmuir : the ACS journal of surfaces and colloids
Sujets:Journal Article Research Support, Non-U.S. Gov't Chlorides Ion Channels Lipid Bilayers Phosphatidylcholines Solvents Water 059QF0KO0R Melitten plus... 20449-79-0 1-palmitoyl-2-oleoylphosphatidylcholine TE895536Y5