Self-assembly of hyperbranched multiarmed PEG-PEI-PLys(Z) copolymer into micelles, rings, and vesicles

Self-assembling of synthesized novel biodegradable hyperbranched amphiphilic poly(ethylene glycol)-polyethylenimine-poly(epsilon-benzyloxycarbonyl-l-lysine) (PEG-PEI-PLys(Z)) in aqueous media is studied. In aqueous media, PLys(Z) is the hydrophobic segment, with PEG and PEI as the hydrophilic segmen...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 25(2009), 17 vom: 01. Sept., Seite 9690-6
1. Verfasser: Guo, Zhaopei (VerfasserIn)
Weitere Verfasser: Li, Yanhui, Tian, Huayu, Zhuang, Xiuli, Chen, Xuesi, Jing, Xiabin
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2009
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Furans Micelles Polymers Solvents Water 059QF0KO0R tetrahydrofuran 3N8FZZ6PY4 mehr... Polyethylene Glycols 3WJQ0SDW1A Polyethyleneimine 9002-98-6 Lysine K3Z4F929H6
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245 1 0 |a Self-assembly of hyperbranched multiarmed PEG-PEI-PLys(Z) copolymer into micelles, rings, and vesicles 
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500 |a Date Revised 01.12.2018 
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500 |a Citation Status MEDLINE 
520 |a Self-assembling of synthesized novel biodegradable hyperbranched amphiphilic poly(ethylene glycol)-polyethylenimine-poly(epsilon-benzyloxycarbonyl-l-lysine) (PEG-PEI-PLys(Z)) in aqueous media is studied. In aqueous media, PLys(Z) is the hydrophobic segment, with PEG and PEI as the hydrophilic segments. It will self-assemble into spherical shape when the selected solvent water is dropped into the common solvent tetrahydrofuran (THF). And when PEG-PEI-PLYS in common solvent is dropped into mixed solvent water and THF, rings will come into being. The spherical and rings are observed by environmental scanning electron microscopy (ESEM) and transmission electron microscopy (TEM). It shows that the size of the sphere is about 100 nm, and the diameter of ring distributes from 400 nm to 10 microm and bigger with the time roll around. It also forms a large vesicle with a thick edge by another method, which is good for drug delivery 
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650 4 |a Research Support, Non-U.S. Gov't 
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650 7 |a tetrahydrofuran  |2 NLM 
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650 7 |a Polyethylene Glycols  |2 NLM 
650 7 |a 3WJQ0SDW1A  |2 NLM 
650 7 |a Polyethyleneimine  |2 NLM 
650 7 |a 9002-98-6  |2 NLM 
650 7 |a Lysine  |2 NLM 
650 7 |a K3Z4F929H6  |2 NLM 
700 1 |a Li, Yanhui  |e verfasserin  |4 aut 
700 1 |a Tian, Huayu  |e verfasserin  |4 aut 
700 1 |a Zhuang, Xiuli  |e verfasserin  |4 aut 
700 1 |a Chen, Xuesi  |e verfasserin  |4 aut 
700 1 |a Jing, Xiabin  |e verfasserin  |4 aut 
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