Oxidized lipids enhance RANKL production by T lymphocytes : implications for lipid-induced bone loss

Osteoporosis is a systemic disease that is associated with increased morbidity, mortality and health care costs. Whereas osteoclasts and osteoblasts are the main regulators of bone homeostasis, recent studies underscore a key role for the immune system, particularly via activation-induced T lymphocy...

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Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 133(2009), 2 vom: 15. Nov., Seite 265-75
1. Verfasser: Graham, Lucia S (VerfasserIn)
Weitere Verfasser: Parhami, Farhad, Tintut, Yin, Kitchen, Christina M R, Demer, Linda L, Effros, Rita B
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2009
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, N.I.H., Extramural Dietary Fats Isoprostanes Lipids Lipoproteins, LDL NF-kappa B OLR1 protein, human Osteoprotegerin Phosphatidylcholines mehr... RANK Ligand Scavenger Receptors, Class E TNFSF11 protein, human Transcription Factor RelA oxidized low density lipoprotein oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine Dinoprostone K7Q1JQR04M 8-isoprostaglandin E2 W1ANC8Q5NW