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231223s2009 xx |||||o 00| ||eng c |
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|a 10.1021/la901591p
|2 doi
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|a pubmed25n0636.xml
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|a eng
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|a Lindhoud, Saskia
|e verfasserin
|4 aut
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|a Salt-induced disintegration of lysozyme-containing polyelectrolyte complex micelles
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|c 2009
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
|b c
|2 rdamedia
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|a ƒa Online-Ressource
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|2 rdacarrier
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|a Date Completed 03.12.2009
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|a Date Revised 30.09.2009
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|a published: Print
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|a Citation Status MEDLINE
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|a The salt-induced disintegration of lysozyme-filled polyelectrolyte complex micelles, consisting of positively charged homopolymers (PDMAEMA150), negatively charged diblock copolymers (PAA42-PAAm417), and lysozyme, has been studied with dynamic light scattering (DLS) and small-angle neutron scattering (SANS). These measurements show that, from 0 to 0.2 M NaCl, both the hydrodynamic radius (Rh) and the core radius (Rcore) decrease with increasing salt concentration. This suggests that the micellar structures rearrange. Moreover, from approximately 0.2 to 0.4 M NaCl the light-scattering intensity is constant. In this salt interval, the hydrodynamic radius increases, has a maximum at 0.3 M NaCl, and subsequently decreases. This behavior is observed in both a lysozyme-containing system and a system without lysozyme. The SANS measurements on the lysozyme-filled micelles do not show increased intensity or a larger core radius at 0.3 M NaCl. This indicates that from 0.2 to 0.4 M NaCl another structure is formed, consisting of just the diblock copolymer and the homopolymer, because at 0.12 M NaCl the lysozyme-PAA42-PAAm417 complex has disintegrated. One may expect that the driving force for the formation of the complex in this salt range is other than electrostatic
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|a Journal Article
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|a Electrolytes
|2 NLM
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|a Micelles
|2 NLM
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|a Polymers
|2 NLM
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|a Salts
|2 NLM
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|a Lipase
|2 NLM
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|a Muramidase
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|a Voorhaar, Lenny
|e verfasserin
|4 aut
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|a de Vries, Renko
|e verfasserin
|4 aut
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|a Schweins, Ralf
|e verfasserin
|4 aut
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|a Cohen Stuart, Martien A
|e verfasserin
|4 aut
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|a Norde, Willem
|e verfasserin
|4 aut
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| 773 |
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|i Enthalten in
|t Langmuir : the ACS journal of surfaces and colloids
|d 1985
|g 25(2009), 19 vom: 06. Okt., Seite 11425-30
|w (DE-627)NLM098181009
|x 1520-5827
|7 nnas
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| 773 |
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|g volume:25
|g year:2009
|g number:19
|g day:06
|g month:10
|g pages:11425-30
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|u http://dx.doi.org/10.1021/la901591p
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