The usefulness of 2D DOSY and 3D DOSY-COSY 1H NMR for mixture analysis : application to genuine and fake formulations of sildenafil (Viagra)

Two-dimensional diffusion ordered spectroscopy (DOSY) (1)H NMR is proposed to analyze drugs that are complex mixtures in order to discriminate genuine from fake formulations. The method was applied to the analysis of 17 formulations of sildenafil, one being genuine Viagra and the others illegally ma...

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Veröffentlicht in:	Magnetic resonance in chemistry : MRC. - 1985. - 47 Suppl 1(2009) vom: 05. Dez., Seite S163-73
1. Verfasser:	Trefi, Saleh (VerfasserIn)
Weitere Verfasser:	Gilard, Véronique, Balayssac, Stéphane, Malet-Martino, Myriam, Martino, Robert
Format:	Online-Aufsatz
Sprache:	English
Veröffentlicht:	2009
Zugriff auf das übergeordnete Werk:	Magnetic resonance in chemistry : MRC
Schlagworte:	Journal Article Complex Mixtures Piperazines Purines Sulfones Sildenafil Citrate BW9B0ZE037