Skewed pattern of Toll-like receptor 4-mediated cytokine production in human neonatal blood : low LPS-induced IL-12p70 and high IL-10 persist throughout the first month of life
Newborns are highly susceptible to infectious diseases, which may be due to impaired immune responses. This study aims to characterize the ontogeny of neonatal TLR-based innate immunity during the first month of life. Cellularity and Toll-like receptor (TLR) agonist-induced cytokine production were...
Ausführliche Beschreibung
Bibliographische Detailangaben
| Veröffentlicht in: | Clinical immunology (Orlando, Fla.). - 1999. - 133(2009), 2 vom: 01. Nov., Seite 228-37
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| 1. Verfasser: |
Belderbos, M E
(VerfasserIn) |
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| Weitere Verfasser: |
van Bleek, G M,
Levy, O,
Blanken, M O,
Houben, M L,
Schuijff, L,
Kimpen, J L L,
Bont, L |
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| Format: | Online-Aufsatz
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| Sprache: | English |
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| Veröffentlicht: |
2009
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| Zugriff auf das übergeordnete Werk: | Clinical immunology (Orlando, Fla.)
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| Schlagworte: | Journal Article
Research Support, Non-U.S. Gov't
Cytokines
IL10 protein, human
IL12A protein, human
IL12B protein, human
Interferon-alpha
Interleukin-12 Subunit p35
Interleukin-12 Subunit p40
Interleukin-6
mehr...
Lipopolysaccharides
TLR4 protein, human
Toll-Like Receptor 4
Toll-Like Receptors
Tumor Necrosis Factor-alpha
Interleukin-10
130068-27-8
Interleukin-12
187348-17-0
Interferon-gamma
82115-62-6 |
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