$Activation of cryptic IgG reactive with BAFF, amyloid beta peptide and GM-CSF during the industrial fractionation of human plasma into therapeutic intravenous immunoglobulins$

Activation of cryptic IgG reactive with BAFF, amyloid beta peptide and GM-CSF during the industrial fractionation of human plasma into therapeutic intravenous immunoglobulins

The mechanisms of therapeutic action of IVIg are still unclear in most autoimmune and inflammatory diseases. IVIg have been shown to bind to a variety of human proteins including BAFF, amyloid beta peptide and GM-CSF. It has been suggested that this autoreactivity could contribute to the therapeutic...

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Détails bibliographiques
Publié dans:	Clinical immunology (Orlando, Fla.). - 1999. - 133(2009), 1 vom: 04. Okt., Seite 52-60
Auteur principal:	St-Amour, Isabelle (Auteur)
Autres auteurs:	Laroche, André, Bazin, Renée, Lemieux, Réal
Format:	Article en ligne
Langue:	English
Publié:	2009
Accès à la collection:	Clinical immunology (Orlando, Fla.)
Sujets:	Journal Article Research Support, Non-U.S. Gov't Amyloid beta-Peptides B-Cell Activating Factor Immunoglobulin G Immunoglobulins, Intravenous TNFSF13B protein, human Ethanol 3K9958V90M Granulocyte-Macrophage Colony-Stimulating Factor 83869-56-1

Accès en ligne	Volltext