Activation of cryptic IgG reactive with BAFF, amyloid beta peptide and GM-CSF during the industrial fractionation of human plasma into therapeutic intravenous immunoglobulins
The mechanisms of therapeutic action of IVIg are still unclear in most autoimmune and inflammatory diseases. IVIg have been shown to bind to a variety of human proteins including BAFF, amyloid beta peptide and GM-CSF. It has been suggested that this autoreactivity could contribute to the therapeutic...
Ausführliche Beschreibung
Bibliographische Detailangaben
| Veröffentlicht in: | Clinical immunology (Orlando, Fla.). - 1999. - 133(2009), 1 vom: 04. Okt., Seite 52-60
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| 1. Verfasser: |
St-Amour, Isabelle
(VerfasserIn) |
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| Weitere Verfasser: |
Laroche, André,
Bazin, Renée,
Lemieux, Réal |
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| Format: | Online-Aufsatz
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| Sprache: | English |
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| Veröffentlicht: |
2009
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| Zugriff auf das übergeordnete Werk: | Clinical immunology (Orlando, Fla.)
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| Schlagworte: | Journal Article
Research Support, Non-U.S. Gov't
Amyloid beta-Peptides
B-Cell Activating Factor
Immunoglobulin G
Immunoglobulins, Intravenous
TNFSF13B protein, human
Ethanol
3K9958V90M
Granulocyte-Macrophage Colony-Stimulating Factor
83869-56-1 |
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