Vaccination with tumor cells pulsed with foreign peptide induces immunity to the tumor itself

EMT-6 mammary carcinoma and B16 melanoma (B16M) cells are lethal and barely immunogenic in syngeneic BALB/c and C57BL/6 mice, respectively. We show that mice vaccinated with tumor cells pulsed with a MHC class I-restricted peptide develop a T cell response, not only to the peptide, but also to the u...

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Bibliographische Detailangaben

Veröffentlicht in:	Clinical immunology (Orlando, Fla.). - 1999. - 133(2009), 1 vom: 15. Okt., Seite 45-51
1. Verfasser:	Schlingmann, Tobias R (VerfasserIn)
Weitere Verfasser:	Rininsland, Frauke H, Bartholomae, Wolf C, Kuekrek, Haydar, Lehmann, Paul V, Tary-Lehmann, Magdalena
Format:	Online-Aufsatz
Sprache:	English
Veröffentlicht:	2009
Zugriff auf das übergeordnete Werk:	Clinical immunology (Orlando, Fla.)
Schlagworte:	Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Cancer Vaccines Histocompatibility Antigens Class I Peptides