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231223s2008 xx ||||| 00| ||eng c |
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|a pubmed25n0633.xml
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|a (DE-627)NLM189774371
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|a (NLM)19578480
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|b ger
|c DE-627
|e rakwb
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|a eng
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| 100 |
1 |
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|a Feller, L
|e verfasserin
|4 aut
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|a MICROPATTERNING OF GOLD SUBSTRATES BASED ON POLY(PROPYLENE SULFIDE-BL-ETHYLENE GLYCOL), (PPS-PEG) BACKGROUND PASSIVATION AND THE MOLECULAR-ASSEMBLY PATTERNING BY LIFT-OFF (MAPL) TECHNIQUE
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|c 2008
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|a Text
|b txt
|2 rdacontent
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|a ohne Hilfsmittel zu benutzen
|b n
|2 rdamedia
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| 338 |
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|a Band
|b nc
|2 rdacarrier
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|a Date Revised 20.10.2021
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|a published: Print
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|a Citation Status PubMed-not-MEDLINE
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|a Poly(propylene sulfide-bl-ethylene glycol (PPS-PEG) is an amphiphilic block copolymer that spontaneously adsorbs onto gold from solution. This results in the formation of a stable polymeric layer that renders the surface protein resistant when an appropriate architecture is chosen. The established molecular assembly patterning by lift-off (MAPL) technique can convert a prestructured resist film into a pattern of biointeractive chemistry and a noninteractive background. Employing the MAPL technique, we produced a micron-scale PPS-PEG pattern on a gold substrate, and then characterized the patterned structure with Time-of-Flight Secondary Ion Mass Spectrometry (TOF-SIMS) and Atomic Force Microscopy (AFM). Subsequent exposure of the PPS-PEG/gold pattern to protein adsorption (full human serum) was monitored in situ; SPR-imaging (i-SPR) shows a selective adsorption of proteins on gold, but not on PPS-PEG areas. Analysis shows a reduction of serum adsorption up to 93% on the PPS-PEG areas as compared to gold, in good agreement with previous analysis of homogenously adsorbed PPS-PEG on gold. MAPL patterning of PPS-PEG block copolymers is straightforward, versatile and reproducible, and may be incorporated into biosensor-based surface analysis methods
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|a Journal Article
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1 |
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|a Bearinger, J P
|e verfasserin
|4 aut
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1 |
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|a Wu, L
|e verfasserin
|4 aut
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1 |
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|a Hubbell, J A
|e verfasserin
|4 aut
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|a Textor, M
|e verfasserin
|4 aut
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| 700 |
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|a Tosatti, S
|e verfasserin
|4 aut
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| 773 |
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|i Enthalten in
|t Surface science
|d 1997
|g 602(2008), 13 vom: 01. Juli, Seite 2305-2310
|w (DE-627)NLM098126490
|x 0039-6028
|7 nnns
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| 773 |
1 |
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|g volume:602
|g year:2008
|g number:13
|g day:01
|g month:07
|g pages:2305-2310
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|a GBV_USEFLAG_A
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|a GBV_ILN_350
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|a AR
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|d 602
|j 2008
|e 13
|b 01
|c 07
|h 2305-2310
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