Increased lymphocyte viability after non-stimulated peripheral blood mononuclear cell (PBMC) culture in patients with X-linked lymphoproliferative disease (XLP)

Survival of lymphocytes after prolonged culture was studied in two asymptomatic XLP patients. Viability of XLP PBMC after 30 days of non-stimulated culture was higher than that of normal controls (N), mainly due to the persistence of CD8 memory lymphocytes. IFNgamma high CD8 T lymphocytes remained h...

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Bibliographische Detailangaben
Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 133(2009), 1 vom: 01. Okt., Seite 86-94
1. Verfasser: Belmonte, Liliana (VerfasserIn)
Weitere Verfasser: Parodi, Cecilia, Bastón, Mariela, Coraglia, Ana, Felippo, Marta, Baré, Patricia, Malbrán, Alejandro, Ruibal-Ares, Beatriz, de E de Bracco, María M
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2009
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Antigens, CD Apoptosis Regulatory Proteins Interleukin-7 Receptor alpha Subunit Intracellular Signaling Peptides and Proteins PDCD1 protein, human Programmed Cell Death 1 Receptor SH2D1A protein, human Signaling Lymphocytic Activation Molecule Associated Protein mehr... Perforin 126465-35-8 Interferon-gamma 82115-62-6