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231223s2009 xx |||||o 00| ||eng c |
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|a 10.1111/j.1939-165X.2009.00159.x
|2 doi
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|a pubmed25n0632.xml
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|a (NLM)19548971
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|a DE-627
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|e rakwb
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|a eng
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| 100 |
1 |
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|a Müller, Kerstin
|e verfasserin
|4 aut
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| 245 |
1 |
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|a Serum thyroxine concentrations in clinically healthy pet guinea pigs (Cavia porcellus)
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|c 2009
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|a Text
|b txt
|2 rdacontent
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|a ƒaComputermedien
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|a ƒa Online-Ressource
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|a Date Completed 17.08.2010
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|a Date Revised 20.10.2016
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|a published: Print-Electronic
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|a Citation Status MEDLINE
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|a BACKGROUND: Guinea pigs (Cavia porcellus) are often presented as patients in veterinary practice. Nevertheless, only limited information is available about endocrine diseases or thyroxine reference values for the species
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|a OBJECTIVE: The aim of this study was to determine serum thyroxine concentrations in a well-defined population of clinically healthy pet guinea pigs
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|a METHODS: Between October 2007 and July 2008, serum samples were collected from 40 clinically healthy guinea pigs of different sexes, ages, and breeds that were presented to our clinic for a general health check or for castration. Pregnant females were excluded from the study. Thyroxine concentration was measured using a chemiluminescence test (Immulite 2000 Canine Total T4)
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|a RESULTS: Thyroxine concentrations ranged from 14.2 to 66.9 nmol/L (1.1-5.2 microg/dL) with a median value of 27.0 nmol/L (2.1 microg/dL). Females (n=16) had significantly (P=.039; Mann-Whitney U-test) lower thyroxine values than castrated males (n=8), whereas no differences were found between females and intact males (n=16) or between intact and castrated males. No significant correlation was found between thyroxine concentration and age
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|a CONCLUSION: This is the first report of serum thyroxine reference values for a well-defined population of healthy pet guinea pigs as measured by a chemiluminescence assay. The results were higher than those previously reported for this species and emphasize the importance of using appropriate reference intervals for the diagnosis of hyperthyroidism
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|a Journal Article
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|a Thyroxine
|2 NLM
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|2 NLM
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1 |
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|a Müller, Elisabeth
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Klein, Ruth
|e verfasserin
|4 aut
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| 700 |
1 |
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|a Brunnberg, Leo
|e verfasserin
|4 aut
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| 773 |
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|i Enthalten in
|t Veterinary clinical pathology
|d 1975
|g 38(2009), 4 vom: 01. Dez., Seite 507-10
|w (DE-627)NLM098159984
|x 1939-165X
|7 nnas
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| 773 |
1 |
8 |
|g volume:38
|g year:2009
|g number:4
|g day:01
|g month:12
|g pages:507-10
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|u http://dx.doi.org/10.1111/j.1939-165X.2009.00159.x
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