Conserved anti-proliferative effect and poor inhibition of TNFalpha secretion by regulatory CD4+CD25+ T cells in patients with systemic lupus erythematosus

A role of natural regulatory CD4+CD25+ T cells in peripheral tolerance has been established, but a causative role of these cells has not been proved in human autoimmune diseases. Functional alterations have been reported in arthritis and contradictory results have been published in systemic lupus er...

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Bibliographische Detailangaben
Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 132(2009), 3 vom: 15. Sept., Seite 385-92
1. Verfasser: Gómez, Jesús (VerfasserIn)
Weitere Verfasser: Prado, Catuxa, López, Patricia, Suárez, Ana, Gutiérrez, Carmen
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2009
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Adrenal Cortex Hormones Antimalarials Interleukin-2 Receptor alpha Subunit Tumor Necrosis Factor-alpha