|
|
|
|
| LEADER |
01000caa a22002652 4500 |
| 001 |
NLM189180501 |
| 003 |
DE-627 |
| 005 |
20250210121103.0 |
| 007 |
cr uuu---uuuuu |
| 008 |
231223s2009 xx |||||o 00| ||eng c |
| 024 |
7 |
|
|a 10.1111/j.1365-2761.2009.01046.x
|2 doi
|
| 028 |
5 |
2 |
|a pubmed25n0631.xml
|
| 035 |
|
|
|a (DE-627)NLM189180501
|
| 035 |
|
|
|a (NLM)19515074
|
| 040 |
|
|
|a DE-627
|b ger
|c DE-627
|e rakwb
|
| 041 |
|
|
|a eng
|
| 100 |
1 |
|
|a Sung, Y Y
|e verfasserin
|4 aut
|
| 245 |
1 |
0 |
|a Feeding Artemia franciscana (Kellogg) larvae with bacterial heat shock protein, protects from Vibrio campbellii infection
|
| 264 |
|
1 |
|c 2009
|
| 336 |
|
|
|a Text
|b txt
|2 rdacontent
|
| 337 |
|
|
|a ƒaComputermedien
|b c
|2 rdamedia
|
| 338 |
|
|
|a ƒa Online-Ressource
|b cr
|2 rdacarrier
|
| 500 |
|
|
|a Date Completed 07.12.2009
|
| 500 |
|
|
|a Date Revised 30.09.2020
|
| 500 |
|
|
|a published: Print-Electronic
|
| 500 |
|
|
|a Citation Status MEDLINE
|
| 520 |
|
|
|a Among their numerous physiological effects, heat shock proteins (Hsps) are potent immunomodulators, a characteristic reflecting their potential as therapeutic agents and which led to their application in combating infection. As an example, the up-regulation of endogenous Hsp70 in the branchiopod crustacean Artemia franciscana (Kellogg) is concurrent with shielding against bacterial infection. To better understand this protective mechanism, gnotobiotic Artemia were fed with Escherichia coli treated to over-produce different prokaryotic Hsps. This was shown to increase larval resistance to experimental Vibrio campbellii exposure. Immunoprobing of Western blots showed that the enhanced resistance to V. campbellii correlated with DnaK production in E coli. A definitive role for DnaK was then demonstrated by feeding Artemia larvae with transformed bacteria over-producing only this protein, although other Hsps such as DnaJ and grpE also provided tolerance against Vibrio infection. Feeding of bacteria synthesizing selected Hsps is therefore suggested as an alternative to antibiotic use as a means of enhancing resistance of Artemia larvae to bacterial infection, which may have potential applications in aquaculture
|
| 650 |
|
4 |
|a Journal Article
|
| 650 |
|
7 |
|a DNA Primers
|2 NLM
|
| 650 |
|
7 |
|a Escherichia coli Proteins
|2 NLM
|
| 650 |
|
7 |
|a HSP70 Heat-Shock Proteins
|2 NLM
|
| 650 |
|
7 |
|a Heat-Shock Proteins
|2 NLM
|
| 650 |
|
7 |
|a Immunologic Factors
|2 NLM
|
| 650 |
|
7 |
|a dnaK protein, E coli
|2 NLM
|
| 650 |
|
7 |
|a EC 3.6.1.-
|2 NLM
|
| 700 |
1 |
|
|a Ashame, M F
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Chen, S
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Macrae, T H
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Sorgeloos, P
|e verfasserin
|4 aut
|
| 700 |
1 |
|
|a Bossier, P
|e verfasserin
|4 aut
|
| 773 |
0 |
8 |
|i Enthalten in
|t Journal of fish diseases
|d 1998
|g 32(2009), 8 vom: 15. Aug., Seite 675-85
|w (DE-627)NLM098166034
|x 1365-2761
|7 nnns
|
| 773 |
1 |
8 |
|g volume:32
|g year:2009
|g number:8
|g day:15
|g month:08
|g pages:675-85
|
| 856 |
4 |
0 |
|u http://dx.doi.org/10.1111/j.1365-2761.2009.01046.x
|3 Volltext
|
| 912 |
|
|
|a GBV_USEFLAG_A
|
| 912 |
|
|
|a SYSFLAG_A
|
| 912 |
|
|
|a GBV_NLM
|
| 912 |
|
|
|a GBV_ILN_350
|
| 951 |
|
|
|a AR
|
| 952 |
|
|
|d 32
|j 2009
|e 8
|b 15
|c 08
|h 675-85
|