Structural stability and increase in size rationalize the efficiency of lipoplexes in serum
We have investigated the effect of serum on nanometric structure, size, surface potential, DNA-binding capacity, and transfection efficiency of DDAB-DOPE/DNA and DC-Chol-DOPE/DNA lipoplexes as a function of membrane charge density and cationic lipid/DNA charge ratio. In the absence of serum, the nan...
Ausführliche Beschreibung
Bibliographische Detailangaben
| Veröffentlicht in: | Langmuir : the ACS journal of surfaces and colloids. - 1992. - 25(2009), 5 vom: 03. März, Seite 3013-21
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| 1. Verfasser: |
Marchini, Cristina
(VerfasserIn) |
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| Weitere Verfasser: |
Montani, Maura,
Amici, Augusto,
Amenitsch, Heinz,
Marianecci, Carlotta,
Pozzi, Daniela,
Caracciolo, Giulio |
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| Format: | Online-Aufsatz
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| Sprache: | English |
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| Veröffentlicht: |
2009
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| Zugriff auf das übergeordnete Werk: | Langmuir : the ACS journal of surfaces and colloids
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| Schlagworte: | Journal Article
1,2-dioleoyl-glycero-3-phosphatidyl ethanolamine
Cations
Lipids
Liposomes
Phosphatidylethanolamines
Quaternary Ammonium Compounds
didodecyldimethylammonium
13146-86-6
DNA
9007-49-2 |
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