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231223s2009 xx |||||o 00| ||eng c |
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|a eng
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| 100 |
1 |
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|a Guan, Jian
|e verfasserin
|4 aut
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| 245 |
1 |
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|a Cooperative dual-stimuli-triggered aggregation of poly-L-histidine-functionalized au nanoparticles
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|c 2009
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|a Text
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|a Date Completed 01.07.2009
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|a Date Revised 21.11.2013
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|a published: Print
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|a Citation Status MEDLINE
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|a Nanoparticles that are responsive to multiple stimuli allow more precise control over the aggregation process and thus the structures and properties of the resulting aggregates. Au nanoparticles functionalized by poly-L-histidine (PLH), a simple polypeptide with a pK(a) value (approximately 6.2) around the physiological pH, are sensitive to pH and temperature simultaneously. The dual stimuli, pH and temperature, must act in a cooperative way to switch the hydrophobic beta-sheet structure of PLH and thus trigger the assembly/disassembly of the Au nanoparticles. The aggregation process and thus the conformation change of PLH can be well recognized by the color change of the Au nanoparticles by naked eyes
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|a Yang, Wensheng
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|i Enthalten in
|t Langmuir : the ACS journal of surfaces and colloids
|d 1985
|g 25(2009), 5 vom: 03. März, Seite 2679-83
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|x 1520-5827
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|g year:2009
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|g day:03
|g month:03
|g pages:2679-83
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