PFGSE-NMR study of pH-triggered behavior in pluronic-ibuprofen solutions

The effect of drug addition and pH variation on Pluronic copolymer solutions has been investigated using pulsed-field gradient (PFG) NMR. Addition of ibuprofen to Pluronic P104 in solution reduced the overall pH from 7.5 to 4.5, as well as promoting micellization; a substantial increase in the hydro...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 25(2009), 12 vom: 16. Juni, Seite 6767-71
1. Verfasser: Foster, Beth (VerfasserIn)
Weitere Verfasser: Cosgrove, Terence, Espidel, Youssef
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2009
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Solutions Poloxamer 106392-12-5 Ibuprofen WK2XYI10QM