Loss of SOCS7 in mice results in severe cutaneous disease and increased mast cell activation
The Suppressor of Cytokine Signaling (SOCS) protein family plays a central role in the negative regulation of cytokine action and has been implicated in the development of atopic diseases. Lack of SOCS7 is associated with severe skin disease in mice. We sought to explore the underlying mechanisms re...
Ausführliche Beschreibung
Bibliographische Detailangaben
Veröffentlicht in: | Clinical immunology (Orlando, Fla.). - 1999. - 132(2009), 2 vom: 01. Aug., Seite 277-84
|
1. Verfasser: |
Knisz, Judit
(VerfasserIn) |
Weitere Verfasser: |
Banks, Alex,
McKeag, Lisa,
Metcalfe, Dean D,
Rothman, Paul B,
Brown, Jared M |
Format: | Online-Aufsatz
|
Sprache: | English |
Veröffentlicht: |
2009
|
Zugriff auf das übergeordnete Werk: | Clinical immunology (Orlando, Fla.)
|
Schlagworte: | Journal Article
Research Support, N.I.H., Extramural
Research Support, N.I.H., Intramural
Research Support, Non-U.S. Gov't
Cytokines
Immunoglobulin G
Interleukin-13
Interleukin-6
Receptors, IgE
Receptors, Interleukin-7
mehr...
SOCS7 protein, mouse
Suppressor of Cytokine Signaling Proteins
Tumor Necrosis Factor-alpha
interleukin-7 receptor, alpha chain
Immunoglobulin E
37341-29-0
Thymic Stromal Lymphopoietin
GT0IL38SP4
TSLP protein, mouse |