Enzyme-activated RGD ligands on functionalized poly(ethylene glycol) monolayers : surface analysis and cellular response

We report on the design, stepwise synthesis, and surface analysis of enzyme-responsive surfaces that present cell adhesive RGD sequences on-demand, that is, by enzymatic hydrolysis of inactive RGD containing precursors that carry cleavable steric blocking groups. These surfaces, incorporating poly(e...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1985. - 25(2009), 13 vom: 07. Juli, Seite 7533-9
1. Verfasser: Todd, Simon J (VerfasserIn)
Weitere Verfasser: Scurr, David J, Gough, Julie E, Alexander, Morgan R, Ulijn, Rein V
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2009
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Ligands Oligopeptides Polyethylene Glycols 3WJQ0SDW1A arginyl-glycyl-aspartic acid 78VO7F77PN