Patients with X-linked lymphoproliferative disease due to BIRC4 mutation have normal invariant natural killer T-cell populations

Human invariant natural killer T cells (iNKT cells) are a unique population of T cells that express an invariantly rearranged T-cell receptor (TCR) composed of TCRValpha24 and TCRVbeta11 chains which recognize glycosphingolipid antigens presented by the CD1d molecule. iNKT cells are absent in patien...

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Veröffentlicht in:Clinical immunology (Orlando, Fla.). - 1999. - 132(2009), 1 vom: 15. Juli, Seite 116-23
1. Verfasser: Marsh, Rebecca A (VerfasserIn)
Weitere Verfasser: Villanueva, Joyce, Kim, Mi-Ok, Zhang, Kejian, Marmer, Dan, Risma, Kimberly A, Jordan, Michael B, Bleesing, Jack J, Filipovich, Alexandra H
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2009
Zugriff auf das übergeordnete Werk:Clinical immunology (Orlando, Fla.)
Schlagworte:Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't X-Linked Inhibitor of Apoptosis Protein XIAP protein, human