Patterning of HeLa cells on a microfabricated Au-coated ITO substrate

HeLa cells were patterned on a microfabricated Au-coated ITO substrate. Part of the Au film was dissolved by the electrochemical wet stamping technique, and the substrate was then immersed in a thiol-terminated methoxy-poly(ethylene glycol) (mPEG-SH) solution for further modification. Self-assembled...

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Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1991. - 25(2009), 9 vom: 05. Mai, Seite 5380-3
1. Verfasser: Jin, Li H (VerfasserIn)
Weitere Verfasser: Yang, Bing Y, Zhang, Li, Lin, Pei L, Cui, Chen, Tang, Jing
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2009
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, Non-U.S. Gov't Tin Compounds Indium 045A6V3VFX Gold 7440-57-5 stannic oxide KM7N50LOS6
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520 |a HeLa cells were patterned on a microfabricated Au-coated ITO substrate. Part of the Au film was dissolved by the electrochemical wet stamping technique, and the substrate was then immersed in a thiol-terminated methoxy-poly(ethylene glycol) (mPEG-SH) solution for further modification. Self-assembled monolayers (SAMs) on the gold island can form cell- and protein-resistant regions on the substrate, and living HeLa cells can adhere to the exposed ITO surface. Single cell patterns could be achieved when the size of a microstructure unit matched that of the cell. The fluorescence experiments further proved that living HeLa cells prefer to attach to the ITO substrate rather than the mPEG-SH-modified gold islands 
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700 1 |a Yang, Bing Y  |e verfasserin  |4 aut 
700 1 |a Zhang, Li  |e verfasserin  |4 aut 
700 1 |a Lin, Pei L  |e verfasserin  |4 aut 
700 1 |a Cui, Chen  |e verfasserin  |4 aut 
700 1 |a Tang, Jing  |e verfasserin  |4 aut 
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