Using a novel loading technique, IL-12 is reported here to be efficiently encapsulated within large multilamellar liposomes. The preclinical efficacy of the cytokine loaded liposomes to deliver IL-12 into human tumors and to reactive tumor-associated T cells in situ is tested using a human tumor xen...
Détails bibliographiques
| Publié dans: | Clinical immunology (Orlando, Fla.). - 1999. - 132(2009), 1 vom: 15. Juli, Seite 71-82
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| Auteur principal: |
Simpson-Abelson, Michelle R
(Auteur) |
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| Autres auteurs: |
Purohit, Vivek S,
Pang, Wing Man,
Iyer, Vandana,
Odunsi, Kunle,
Demmy, Todd L,
Yokota, Sandra J,
Loyall, Jenni L,
Kelleher, Raymond J Jr,
Balu-Iyer, Sathy,
Bankert, Richard B |
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| Format: | Article en ligne
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| Langue: | English |
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| Publié: |
2009
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| Accès à la collection: | Clinical immunology (Orlando, Fla.)
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| Sujets: | Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Ki-67 Antigen
Liposomes
Interleukin-12
187348-17-0 |
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