TRAIL, DR4 and DR5 are upregulated in kidneys from patients with lupus nephritis and exert proliferative and proinflammatory effects
We have previously reported that TRAIL is upregulated on T cells from patients with lupus and that T cell associated TRAIL enhances autoimmune parameters in a murine model of lupus. Whether TRAIL/TRAIL-R interaction plays a role in organ involvement such as lupus nephritis has not yet been assessed....
Ausführliche Beschreibung
Bibliographische Detailangaben
| Veröffentlicht in: | Clinical immunology (Orlando, Fla.). - 1999. - 132(2009), 1 vom: 15. Juli, Seite 32-42
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| 1. Verfasser: |
Nguyen, Vinh
(VerfasserIn) |
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| Weitere Verfasser: |
Cudrici, Cornelia,
Zernetkina, Valentina,
Niculescu, Florin,
Rus, Horea,
Drachenberg, Cynthia,
Rus, Violeta |
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| Format: | Online-Aufsatz
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| Sprache: | English |
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| Veröffentlicht: |
2009
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| Zugriff auf das übergeordnete Werk: | Clinical immunology (Orlando, Fla.)
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| Schlagworte: | Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Inflammation Mediators
Receptors, TNF-Related Apoptosis-Inducing Ligand
Receptors, Tumor Necrosis Factor
TNF-Related Apoptosis-Inducing Ligand
TNFRSF10A protein, human
TNFSF10 protein, human
Tumor Necrosis Factor-alpha
mehr...
Interferon-gamma
82115-62-6 |
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