A Nematode Growth Factor from Baker's Yeast

An extract prepared from commercially available yeast supported maturation of the free-living nematode Caenorhabditis briggsae. The extract can be used to supplement a chemically defined medium or, after a limited dialysis, as a complete medium. Several biologically active fractions were prepared; t...

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Veröffentlicht in:Journal of nematology. - 1969. - 2(1970), 1 vom: 13. Jan., Seite 93-8
1. Verfasser: Buecher, E J (VerfasserIn)
Weitere Verfasser: Hansen, E L, Gottfried, T
Format: Aufsatz
Sprache:English
Veröffentlicht: 1970
Zugriff auf das übergeordnete Werk:Journal of nematology
Schlagworte:Journal Article Axenic culture Caenorhabditis briggsae Particle formation Ribosomes
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100 1 |a Buecher, E J  |e verfasserin  |4 aut 
245 1 2 |a A Nematode Growth Factor from Baker's Yeast 
264 1 |c 1970 
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500 |a Date Completed 14.07.2011 
500 |a Date Revised 20.10.2021 
500 |a published: Print 
500 |a ErratumIn: J Nematol. 1971 Jan;3(1):100.. - PMID 19322353 
500 |a Citation Status PubMed-not-MEDLINE 
520 |a An extract prepared from commercially available yeast supported maturation of the free-living nematode Caenorhabditis briggsae. The extract can be used to supplement a chemically defined medium or, after a limited dialysis, as a complete medium. Several biologically active fractions were prepared; those containing larger amounts of ribonucleic acid (RNA) had greater biological activity, the most active being a pellet resuspended after centrifugation at 30,000 x g for 30 min. This fraction could be substituted for serum in a medium which supports the maturation of the animal parasites Trichinella spiralis and Hymenolepis nana. Addition of protamine sulfate decreased the RNA content, leaving inactive protein fractions which could be reactivated by specific treatments that caused protein precipitation. It is postulated that biological activity is associated with protein sedimented with ribosomes 
650 4 |a Journal Article 
650 4 |a Axenic culture 
650 4 |a Caenorhabditis briggsae 
650 4 |a Particle formation 
650 4 |a Ribosomes 
700 1 |a Hansen, E L  |e verfasserin  |4 aut 
700 1 |a Gottfried, T  |e verfasserin  |4 aut 
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