T-bet expression is regulated by EGR1-mediated signaling in activated T cells
T-bet is a Th1-specific transcription factor that is directly involved in three important pathways for Th1 cell differentiation, namely TCR signaling, and the IFN-gamma-STAT1 and IL-12-STAT4 pathways. A recent study also showed that T-bet plays a vital role in innate immunity. However, the molecular...
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Détails bibliographiques
| Publié dans: | Clinical immunology (Orlando, Fla.). - 1999. - 131(2009), 3 vom: 15. Juni, Seite 385-94
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| Auteur principal: |
Shin, Hyun-Jin
(Auteur) |
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| Autres auteurs: |
Lee, Jee-Boong,
Park, Sung-Hwan,
Chang, Jun,
Lee, Chang-Woo |
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| Format: | Article en ligne
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| Langue: | English |
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| Publié: |
2009
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| Accès à la collection: | Clinical immunology (Orlando, Fla.)
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| Sujets: | Journal Article
Research Support, Non-U.S. Gov't
EGR1 protein, human
Early Growth Response Protein 1
Receptors, Antigen, T-Cell
T-Box Domain Proteins
T-bet Transcription Factor |
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