T-bet expression is regulated by EGR1-mediated signaling in activated T cells

T-bet is a Th1-specific transcription factor that is directly involved in three important pathways for Th1 cell differentiation, namely TCR signaling, and the IFN-gamma-STAT1 and IL-12-STAT4 pathways. A recent study also showed that T-bet plays a vital role in innate immunity. However, the molecular...

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Veröffentlicht in:	Clinical immunology (Orlando, Fla.). - 1999. - 131(2009), 3 vom: 15. Juni, Seite 385-94
1. Verfasser:	Shin, Hyun-Jin (VerfasserIn)
Weitere Verfasser:	Lee, Jee-Boong, Park, Sung-Hwan, Chang, Jun, Lee, Chang-Woo
Format:	Online-Aufsatz
Sprache:	English
Veröffentlicht:	2009
Zugriff auf das übergeordnete Werk:	Clinical immunology (Orlando, Fla.)
Schlagworte:	Journal Article Research Support, Non-U.S. Gov't EGR1 protein, human Early Growth Response Protein 1 Receptors, Antigen, T-Cell T-Box Domain Proteins T-bet Transcription Factor