T-bet expression is regulated by EGR1-mediated signaling in activated T cells
T-bet is a Th1-specific transcription factor that is directly involved in three important pathways for Th1 cell differentiation, namely TCR signaling, and the IFN-gamma-STAT1 and IL-12-STAT4 pathways. A recent study also showed that T-bet plays a vital role in innate immunity. However, the molecular...
Ausführliche Beschreibung
Bibliographische Detailangaben
| Veröffentlicht in: | Clinical immunology (Orlando, Fla.). - 1999. - 131(2009), 3 vom: 15. Juni, Seite 385-94
|
|---|
| 1. Verfasser: |
Shin, Hyun-Jin
(VerfasserIn) |
|---|
| Weitere Verfasser: |
Lee, Jee-Boong,
Park, Sung-Hwan,
Chang, Jun,
Lee, Chang-Woo |
|---|
| Format: | Online-Aufsatz
|
|---|
| Sprache: | English |
|---|
| Veröffentlicht: |
2009
|
|---|
| Zugriff auf das übergeordnete Werk: | Clinical immunology (Orlando, Fla.)
|
|---|
| Schlagworte: | Journal Article
Research Support, Non-U.S. Gov't
EGR1 protein, human
Early Growth Response Protein 1
Receptors, Antigen, T-Cell
T-Box Domain Proteins
T-box transcription factor TBX21 |
|---|