Reduced sterol-phospholipid recognition in curved fluid bilayers

Nearest-neighbor recognition experiments have been carried out in fluid liposomal membranes made from 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) and cholesterol using exchangeable dimers derived from 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine and cholesterol. In cholesterol-rich bilaye...

Ausführliche Beschreibung

Bibliographische Detailangaben
Veröffentlicht in:Langmuir : the ACS journal of surfaces and colloids. - 1992. - 25(2009), 8 vom: 21. Apr., Seite 4328-30
1. Verfasser: Mitomo, Hideyuki (VerfasserIn)
Weitere Verfasser: Chen, Wen-Hua, Regen, Steven L
Format: Online-Aufsatz
Sprache:English
Veröffentlicht: 2009
Zugriff auf das übergeordnete Werk:Langmuir : the ACS journal of surfaces and colloids
Schlagworte:Journal Article Research Support, N.I.H., Extramural Lipid Bilayers Lipids Liposomes Phospholipids Sterols 1,2-Dipalmitoylphosphatidylcholine 2644-64-6 Cholesterol 97C5T2UQ7J
LEADER 01000naa a22002652 4500
001 NLM187228612
003 DE-627
005 20231223175638.0
007 cr uuu---uuuuu
008 231223s2009 xx |||||o 00| ||eng c
024 7 |a 10.1021/la900346p  |2 doi 
028 5 2 |a pubmed24n0624.xml 
035 |a (DE-627)NLM187228612 
035 |a (NLM)19301879 
040 |a DE-627  |b ger  |c DE-627  |e rakwb 
041 |a eng 
100 1 |a Mitomo, Hideyuki  |e verfasserin  |4 aut 
245 1 0 |a Reduced sterol-phospholipid recognition in curved fluid bilayers 
264 1 |c 2009 
336 |a Text  |b txt  |2 rdacontent 
337 |a ƒaComputermedien  |b c  |2 rdamedia 
338 |a ƒa Online-Ressource  |b cr  |2 rdacarrier 
500 |a Date Completed 07.07.2009 
500 |a Date Revised 20.10.2021 
500 |a published: Print 
500 |a Citation Status MEDLINE 
520 |a Nearest-neighbor recognition experiments have been carried out in fluid liposomal membranes made from 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) and cholesterol using exchangeable dimers derived from 1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine and cholesterol. In cholesterol-rich bilayers, the association between these two exchangeable lipids was reduced as the curvature of the membrane increases; that is, when the diameter of the liposomes was below ca. 200 nm. In sharp contrast, the mixing of these exchangeable lipids was close to random in the cholesterol-poor membranes, regardless of their curvature. The biological implications of these findings are briefly discussed 
650 4 |a Journal Article 
650 4 |a Research Support, N.I.H., Extramural 
650 7 |a Lipid Bilayers  |2 NLM 
650 7 |a Lipids  |2 NLM 
650 7 |a Liposomes  |2 NLM 
650 7 |a Phospholipids  |2 NLM 
650 7 |a Sterols  |2 NLM 
650 7 |a 1,2-Dipalmitoylphosphatidylcholine  |2 NLM 
650 7 |a 2644-64-6  |2 NLM 
650 7 |a Cholesterol  |2 NLM 
650 7 |a 97C5T2UQ7J  |2 NLM 
700 1 |a Chen, Wen-Hua  |e verfasserin  |4 aut 
700 1 |a Regen, Steven L  |e verfasserin  |4 aut 
773 0 8 |i Enthalten in  |t Langmuir : the ACS journal of surfaces and colloids  |d 1992  |g 25(2009), 8 vom: 21. Apr., Seite 4328-30  |w (DE-627)NLM098181009  |x 1520-5827  |7 nnns 
773 1 8 |g volume:25  |g year:2009  |g number:8  |g day:21  |g month:04  |g pages:4328-30 
856 4 0 |u http://dx.doi.org/10.1021/la900346p  |3 Volltext 
912 |a GBV_USEFLAG_A 
912 |a SYSFLAG_A 
912 |a GBV_NLM 
912 |a GBV_ILN_22 
912 |a GBV_ILN_350 
912 |a GBV_ILN_721 
951 |a AR 
952 |d 25  |j 2009  |e 8  |b 21  |c 04  |h 4328-30